Adaptive time-frequency parametrization in pharmaco EEG
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Adaptive time-frequency approximations offer description of local signal's structures in terms of their time and frequency coordinates, widths and amplitudes. All these parameters can be used to select and study EEG structures like sleep spindles or slow wave activity with high resolution. Such a detailed description of relevant structures improves sensitivity of the traditionally used spectral power estimates and opens new possibilities of investigation. These advantages are presented on a double-blind test of influence of zolpidem and midazolam on sleep EEG, including comparison with the traditional approach. Observed decrease of frequency of the slow wave activity under the influene of sleep-inducing drugs gives an example of an effect elusive to the classical methodology.
Adaptive time-frequency parametrization in pharmaco EEG, P.J. Durka, W. Szelenberger, K.J. Blinowska, W. Androsiuk, M. Myszka. Journal of Neuroscience Methods 117, pp. 65-71, 2002
Oct 17, 2003 01:30 PM
